Messina is a harbor city in northeast Sicily, Italy. It is the capital of the Italian Metropolitan City of Messina, and has close ties with Reggio Calabria. The city's main resources are its seaports (commercial and military shipyards), cruise tourism, commerce, and agriculture (wine production and cultivating lemons, oranges, mandarin oranges, and olives). The city has been a Roman Catholic Archdiocese and Archimandrite seat since 1548 and is home to a locally important international fair. The city has the University of Messina, founded in 1548 by Ignatius of Loyola. Messina has a light rail system, Tranvia di Messina, that was opened on 3 April 2003. This line is 7.7 kilometres (4.8 mi) and links the city's central railway station with the city centre and harbour. The city is home to a significant Greek-speaking minority, rooted in its history and officially recognised.

Rhodes is the largest of the Dodecanese islands in terms of land area and also the island group's historical capital. Administratively the island forms a separate municipality within the Rhodes regional unit, which is part of the South Aegean administrative region. It is located northeast of Crete, southeast of Athens and just off the Anatolian coast of Turkey. Rhodes' nickname is The island of the Knights, named after the Knights of Saint John of Jerusalem, who once conquered the land. Historically, Rhodes was famous worldwide for the Colossus of Rhodes, one of the Seven Wonders of the Ancient World. The Medieval Old Town of the City of Rhodes has been declared a World Heritage Site. Today, it is one of the most popular tourist destinations in Europe.

Mykonos is a Greek island, part of the Cyclades, lying between Tinos, Syros, Paros and Naxos. The island spans an area of 85.5 km2 (33 sq mi) and rises to an elevation of 341 m (1,119 ft) at its highest point. The island is composed primarily of granite. It has little natural fresh water and relies on the desalination of sea water in order to meet the needs of its population. There are 9,320 inhabitants (2001) most of whom live in the largest town, Mykonos, also known as Chora, which lies on the west coast. Mykonos is one of the most cosmopolitan islands in Greece, known for its diverse and intense nightlife as evidenced by a vast number of bars and nightclubs. Mykonos is also known for its beaches. The island has an international airport, and is a frequent destination for cruise ships. 

Naples is a city in Italy; it is the capital of the region of Campania and of the province of Naples. Known for its rich history, art, culture, architecture, music, and gastronomy, Naples has played an important role in the Italian peninsula and beyond for much of its existence, which began more than 2,800 years ago. Situated on the west coast of Italy by the Gulf of Naples, the city is located halfway between two volcanic areas, Mount Vesuvius and the Phlegraean Fields. Naples has the fourth-largest urban economy in Italy, after Milan, Rome and Turin. It is the world's 103rd-richest city by purchasing power, with an estimated 2011 GDP of US$83.6 billion. The port of Naples is one of the most important in Europe, and has the world's second-highest level of passenger flow, after the port of Hong Kong. The city has long been a major cultural centre with a global sphere of influence, particularly during the Renaissance and Enlightenment eras. In the immediate vicinity of Naples are numerous culturally and historically significant sites, including the Palace of Caserta and the Roman ruins ofPompeii and Herculaneum. Culinarily, it is synonymous with pizza, which originated in the city.

Athens is the capital and largest city of Greece. Athens dominates the Attica periphery and it is one of the world's oldest cities, as its recorded history spans around 3,400 years. The city is widely referred to as the cradle of Western civilization and the birthplace of democracy, largely because of its cultural and political impact on the European continent and in particular the Romans. In modern times, Athens is a large cosmopolitan metropolis and central to economic, financial, industrial, maritime, political and cultural life in Greece. Its compact downtown, north of campus, is alive with clubs, bars, restaurants, galleries and – of course – record stores; Broad Street in particular is lined with arty shops.

Civitavecchia is a town and comune of the Metropolitan City of Rome in the central Italian region of Lazio. A sea port on the Tyrrhenian Sea, the name ''Civitavecchia'' means "ancient town". The modern city was built over a pre-existing Etruscan settlement. The massive Forte Michelangelo was first commissioned from Donato Bramante by Pope Julius II, to defend the port of Rome. The upper part of the "maschio" tower, however, was designed by Michelangelo, whose name is generally applied to the fortress. North of the city at Ficoncella are the Terme Taurine baths frequented by Romans and still popular with the Civitavecchiesi. The modern name stems from the common fig plants among the various pools. And also next to the town is the location of the cruise ship docks. All major cruise lines start and end their cruises at this location, and others stop for shore excursion days that allow guests to see Rome and Vatican sights, which are ninety minutes away.

Chania is the second largest city of Crete and the capital of the Chania regional unit. Lies along the north coast of the island, about 70 km (43 mi) west of Rethymno and 145 km (90 mi) west of Heraklion, it is one of the two places you are most likely to see on arriving in Crete. It is breathtaking - that is to say much of the Chania you will want to see is clustered close to the harbour - old buildings, museums, churches and crafts shops.