Seville is the artistic, cultural, and financial capital of southern Spain. It is the capital of the autonomous community of Andalusia and of the province of Seville. It is situated on the plain of the River Guadalquivir, with an average elevation of 7 metres (23 ft) above sea level. The inhabitants of the city are known as sevillanos (feminine form: sevillanas) or hispalenses, following the Roman name of the city, Hispalis. The tapas scene is one of the main cultural attractions of the city: people go from one bar to another, enjoying small dishes called tapas (literally "lids" or "covers" in Spanish, referring to their probable origin as snacks served on small plates used to cover drinks). Local specialities include fried and grilled seafood (including squid, choco (cuttlefish), swordfish, marinated dogfish, and ortiguillas), grilled and stewed meat, spinach with chickpeas, Jamón ibérico, lamb kidneys in sherry sauce, snails, caldo de puchero, and gazpacho. A sandwich known as a serranito is the typical and popular version of fast food.

Granada is a city and the capital of the province of Granada, in the autonomous community of Andalusia, Spain. Rich in history and culture, Granada is arguably the single most worthwhile city in Spain for visitors. In addition to a rich multicultural history, the Alhambra (a grand, sprawling hilltop fortress complex encompassing royal palaces) and other monuments, a student-driven nightlife, and skiing and trekking in the nearby Sierra Nevada, Granada offers a break from the summer heat of other Andalusian cities such as Córdoba or Seville.

The capital of Portugal, Lisbon (Portuguese: Lisboa) has experienced a renaissance in recent years, with a contemporary culture that is alive and thriving and making its mark in today's Europe. Perched on the edge of the Atlantic Ocean, Lisbon is one of the rare Western European cities that faces the ocean and uses water as an element that defines the city. Lisbon enchants travellers with its white-bleached limestone buildings, intimate alleyways, and an easy-going charm that makes it a popular year-round destination.

Málaga is a large city in the southern Spanish region of Andalucia and capital of the Malaga Province. The largest city on the Costa del Sol, Malaga has a typical Mediterranean climate and is also known as the birthplace of famous Spanish artist Pablo Picasso. The city offers beaches, hiking, architectural sites, art museums, excellent shopping and cuisine. While more laid back than Madrid or Barcelona, Malaga is still the center and transport hub for the hugely popular Costa del Sol region, which is flooded with tourists in the summer, and the city has certainly cashed in on the sun and sand, with lots of new construction as well as hotels and facilities geared to tourists. However, Malaga also offers some genuinely interesting historical and cultural attractions in its old city and its setting on the coast is still beautiful.

Barcelona – Spain's enchanting capital, second largest and most populous city. It is a huge city that vibrates with life, and there’s certainly not another city in the country to touch it for its sheer style, looks or energy. It is one of the world's leading tourist, economic, trade fair and cultural centers, and its influence in commerce, education, entertainment, media, fashion, science, and the arts all contribute to its status as one of the world's major global cities. Barcelona is home to masterpieces of many great architects – the most famous of which is Antoni Gaudí. 

Valencia is the most populous city of the Autonomous Community of Valencia and the third largest city in Spain, with a population of 809,267 in 2010. It is the 15th-most populous municipality in the European Union. It is integrated into an industrial area on the Costa del Azahar. Its historic centre is one of the largest in Spain, with approximately 169 hectares; this heritage of ancient monuments, views and cultural attractions makes Valencia one of the country's most popular tourist destinations!

Cartagena is a Spanish city and a majornaval station located in the Region of Murcia, by the Mediterranean coast, south-eastern Spain. The metropolitan area of Cartagena, known as Campo de Cartagena, has a population of 409,586 inhabitants. Cartagena has been inhabited for over two millennia, being founded around 227 BC by the Carthaginian Hasdrubal the Fair as Qart Hadasht, the same name as the original city of Carthage. Much of the historical weight of Cartagena in the past goes to its coveted defensive port, one of the most important in the western Mediterranean. As far back as the 16th century it was one of the most important naval ports in Spain, together with Ferrol in the North. It is still an important naval seaport, the main military haven of Spain, and is home to a large naval shipyard. The confluence of civilizations as well as its strategic harbour, together with the rise of the local mining industry is manifested by a unique artistic heritage, with a number of landmarks such as the Roman Theatre, the second largest of the Iberian Peninsulaafter the one in Mérida, an abundance of Phoenician, Roman, Byzantine and Moorish remains, and a plethora of Art Nouveaubuildings, a result of the bourgeoisie from the early 20th century. Cartagena is now established as a major cruise ship destination in the Mediterranean and an emerging cultural focus. It is the first of a number of cities that eventually have been named Cartagena, most notably Cartagena de Indias (Cartagena of the Indies) in Colombia.